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https://doi.org/10.53941/mi.2025.100006
Chen, Y., Yan, E., & Xia, Y. Noble-Metal Nanocrystals: From Synthesis to Biomedical Applications. Materials and Interfaces. 2025. doi: https://doi.org/10.53941/mi.2025.100006
Volume 2, Issue 1, 2025
Copyright (c) 2025 by the authors.
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This work is licensed under a Creative Commons Attribution 4.0 International License.

Perspective

Noble-Metal Nanocrystals: From Synthesis to Biomedical Applications

Yidan Chen 1, Emily Yan 2, and Younan Xia 2,*

1 School of Materials Science and Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA

2 Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA

* Correspondence: younan.xia@bme.gatech.edu

Received: 24 February 2025; Accepted: 26 February 2025; Published: 28 February 2025

Abstract: Noble metals hold promises for a variety of biomedical applications due to their unique physical and biochemical properties. To unlock this potential, a significant amount of research has been dedicated to the controlled synthesis of noble-metal nanocrystals over the past two decades, with a particular emphasis on the production of Au and Ag nanocrystals with diverse and well-controlled shapes. The successful synthesis of noble-metal nanocrystals with tunable sizes, shapes, and morphologies allows researchers to explore their use in a range of biomedical applications, including contrast enhancement for an array of bioimaging modalities, facilitating stimuli-responsive drug delivery, and functioning as antimicrobial or anticancer agents.

Keywords:

noble metals nanocrystal synthesis biomedical applications

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