Acne is the most common dermatologic complication encountered by transgender men during the transition phase. It affects approximately 1 in 3 individuals, and they consider it severe in about 1 in 3 cases as well, mainly transgender men receiving testosterone. There are no specific recommendations for the management of acne in transgender patients but care generally follows the same approach as for cisgender patients. Prescribing isotretinoin is particular in transgender men because clinicians must inquire about their genital anatomy and sexual practices. Testosterone therapy and amenorrhea in a transgender man with native female reproductive organs do not eliminate the risk of pregnancy. Contraception with regular pregnancy testing may therefore be necessary.



