Considering that the relative attitude between the subsystems of space solar power station has the characteristic of periodic continuous change, the adjustment strategy of space large-span parallel cable mechanism is studied. Taking OMEGA (Orb-shape Membrane Energy Gathering Array) type space solar power station as the research object, the motion relationship between subsystems is analyzed. The kinematic analysis of the cable mechanism is carried out, and the variation rule of cable length is obtained. With the minimum variance of cable force as the optimization objective, the smoothness of cable force variation and the lightweight of cable as the design criteria, the optimal installation position of cable and the optimal adjustment strategy of cable mechanism are optimized. Through simulation analysis, the parallel cable mechanism proposed in this paper changes smoothly, which is suitable for the adjustment strategy of the relative attitude of the space solar power station subsystem.