Quantum Information Systems (QIS) have emerged as a transformative paradigm, integrating the principles of quantum mechanics with advanced computational and communication technologies to address complex problems beyond the capabilities of classical systems. This review provides a comprehensive synthesis of current developments, beginning with the foundational principles that define QIS, including its theoretical underpinnings, quantum state representations, and computational frameworks. It then examines advances in quantum computing for QIS, with a focus on hardware architectures, the design and optimization of core algorithms, and the computational advantages over classical approaches. The discussion extends to quantum machine learning for QIS, exploring hybrid quantum–classical learning models, quantum data encoding techniques, and optimization strategies. Finally, it surveys diverse application domains, such as finance, industrial information integration, energy systems, healthcare, and intelligent transportation. In addition, the paper highlights pressing technological, data-centric, algorithmic, and ecosystem-level challenges, and discusses future trajectories shaped by innovations such as quantum blockchain, quantum artificial intelligence, and decentralized QIS. Through a structured and integrative analysis, this work aims to provide a roadmap for researchers and practitioners navigating the rapidly evolving QIS landscape.



