RC/
Articles/
2601002903
  • Open Access
  • Review

Furfural as a Bio-Based Platform Molecule in Industry: Feedstocks and New Chemistries

  • James H. Clark 1,2,   
  • Roxana A. Milescu 2,*

Received: 07 Dec 2025 | Revised: 08 Jan 2026 | Accepted: 22 Jan 2026 | Published: 10 Feb 2026

Abstract

Furfural is a versatile platform molecule, easily obtained in often very good yields from a variety of biomass and now being manufactured in several global locations. Several process innovations and extensive catalyst development work, largely disclosed in patents, have made manufacturing processes commercially viable and sustainable. Feedstock selection and strategies for furfural manufacture are examined, including biphasic systems, solid acid catalysis, deep eutectic solvents, microwave-assisted processes, and integrated biorefinery concepts designed to maximise overall biomass valorisation. The review explores the dominant reaction classes used to upgrade furfural—hydrogenation, oxidation, decarbonylation, and nitrogen-incorporation—emphasizing catalytic strategies and process architectures that enable selective, scalable, and industrially relevant transformations. Particular attention is given to furfuryl alcohol and its derivatives, emerging routes to cyclopentanone and 2-methylfuran, and oxidation pathways to furoic acid, maleic acid, and furan dicarboxylic acids. The growing importance of furfural as a precursor to polymer monomers, especially in routes to FDCA and polyethylene furanoate (PEF) as bio-based alternatives to PET, is analysed in detail. By integrating patent literature, industrial case studies, and recent academic advances, this review positions furfural as a central hub in future lignocellulosic biorefineries and highlights the innovations that are likely to define its next phase of commercial deployment. By integrating patent literature, industrial case studies, and recent academic advances, this review positions furfural as a central hub in future lignocellulosic biorefineries and highlights the innovations that are likely to define its next phase of commercial deployment. 

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DOI
10.53941/rc.2026.100001
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Volume 2, Issue 1
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Clark, J. H.; Milescu, R. A. Furfural as a Bio-Based Platform Molecule in Industry: Feedstocks and New Chemistries. Renewable Chemistry 2026, 2 (1), 1. https://doi.org/10.53941/rc.2026.100001.
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