• Open Access
  • Editorial

Time for a Drastic Paradigm Shift in the Management of Cardiac Failure Patients

  • Daniel Loisance 1,2

Received: 04 Mar 2026 | Accepted: 04 Mar 2026 | Published: 18 Mar 2026

References 

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    Leyva, F.; Israel, C.W.; Singh, J. Declining Risk of Sudden Cardiac Death in Heart Failure: Fact or Myth? Circulation 2023, 147, 759–767.

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    Khush, K.K.; Hsich, E.; Potena, L.; et al. The International Thoracic Organ Transplant Registry of the International Society for Heart and Lung Transplantation: Thirty-eighth adult heart transplantation report—2021. J. Heart Lung Transplant. 2021, 40, 1035–1049.

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    Chung, B.B.; Sayer, G.; Uriel, N. Mechanical circulatory support devices: Methods to optimize hemodynamics during use. Expert Rev. Med. Devices 2017, 15, 343–353.

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    Masarone, D.; Gravino, R.; Falco, L.; et al. The Total Artificial Heart: A Historical Perspective. J. Clin. Med. 2025, 14, 6290.

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    Sanz-Ruiz, R.; Emerson, C.; Perin, E.C.; et al. Cell therapy for heart failure: Lessons learned from SCIENCE. Eur. J. Heart Fail. 2023, 25, 588–590.

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    Griffith, B.P.; Corbin, E.; Goerlich, C.E.; et al. Genetically Modified Porcine-to-Human Cardiac Xenotransplantation. New Engl. J. Med. 2022, 387, 35–44.

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    Loupy, A.; Sablik, M.; Khush, K. Advancing patient monitoring, diagnostics and treatment strategies for transplant precision medecine. Lancet 2025, 406, 389–402.

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How to Cite
Loisance, D. Time for a Drastic Paradigm Shift in the Management of Cardiac Failure Patients. iCirculation 2026, 1 (1), 1. https://doi.org/10.53941/icirculation.2026.100001.
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