2508001143
  • Open Access
  • Review

A Comprehensive Review of the Ethnopharmacology, Phytochemistry, and Therapeutic Medicinal Potential of Nyctanthes arbortristis L.

  • Pawan Kumar Sagar 1, *,   
  • Aditya Sagar 2,   
  • Ayesha Akhtar 3,   
  • Singh Jitendra Pal 3,   
  • Kumar Mukash 3,   
  • Jayanthy A. 3,   
  • Rajendra Murugeswaran 4,   
  • Khan Asma 1

Received: 09 Apr 2025 | Revised: 06 May 2025 | Accepted: 11 Aug 2025 | Published: 19 Aug 2025

Abstract

Ethnopharmacological, phytochemistry, therapeutic, and medicinal potential studies of Ayurvedic, Siddha, and Unani (ASU) medicinal natural single drugs/products are a significant and challenging task on a global level. There is a need for more advanced investigative research studies and screening of scientific research data to emphasize and explore the ethno-pharmacology, phytochemistry, and therapeutic medicinal potential values of ASU plants/products, including authentication, medicinal, and therapeutic aspects. Nyctanthes arbortristis L. is a tree used to treat various health and wellness issues and therapeutic illnesses in mankind since ancient times. This study aims to evaluate the ethno-pharmacological, phytochemistry, therapeutic, and medicinal potential values through a comprehensive review of the plant NAT. This comprehensive review gathered and analyzed studies, information on NAT from databases such as Web of Science, Scopus, Google Scholar, PubMed, ScienceDirect, Springer, and other scientific literature accessed from various electronic search engine databases. The review studies explored and authenticated the ethno-pharmacology, phytochemistry, and therapeutic medicinal potential values of NAT using standard review methods. The ethno-pharmacological, phytochemistry, and therapeutic medicinal potential values, along with the divine curative healing properties, have been found to be effective, consistent, and rich sources of novel bioactive compounds in the study medicinal plant. NAT has shown significant ethno-pharmacological, phytochemistry, biodiversity, and therapeutic medicinal potential activity. This study’s herbal research data is helpful in confirming and revalidating the development of drug standards, pharmacovigilance, and research on therapeutic medicinal values that may be helpful to treat various conditions such as antiarthritic activity, antistress activity, anticancer activities, cytotoxic activities, anti-inflammatory, hypoglycemic and hypolipidemic activity, antiviral activity, antibacterial activity, antimicrobial activity, antifungal activity, antiulcer activity, antipyretic, analgesic activity, and obstinate sciatica disorder, among others.

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Sagar, P. K.; Sagar, A.; Akhtar, A.; Pal, S. J.; Mukash, K.; A., J.; Murugeswaran, R.; Asma, K. A Comprehensive Review of the Ethnopharmacology, Phytochemistry, and Therapeutic Medicinal Potential of Nyctanthes arbortristis L.. Journal of Medicinal Natural Products 2025, 2 (3), 100018. https://doi.org/10.53941/jmnp.2025.100018.
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