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Global Research Trends and Hotspots in Meibomian Gland Dysfunction (2014–2023): A Comprehensive Bibliometric and Visualization Analysis
Qian Liu1
Fangkun Zhao2
Jun Liu1
Minmei Guo1
Chengyu Jiang1
Tao Yu1
Ting Wang1
Tzu-Cheng Sung1
Jun Kong2
Akon Higuchi1, 3, *
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Submitted: 21 Jan 2025 | Revised: 11 Mar 2025 | Accepted: 12 Mar 2025 | Published: 17 Mar 2025

Abstract

This study aimed to explore the global research landscape, emerging hotspots, and advancements in Meibomian Gland Dysfunction (MGD) over the last decade through a bibliometric and visualization analysis for regenerative medicine strategy to treat MGD patients. Data were collected from the Web of Science Core Collection, covering the period from 2014 to 2023. VOSviewer and CiteSpace were used to analyze and visualize publication trends, contributions by countries and institutions, co-authorship analysis, journal impact, and keyword co-occurrence. Emerging topics were identified using keyword citation burst analysis. A total of 1271 publications were included. Four major research hotspots were identified: (1) etiology and pathogenesis, (2) advancements in diagnostic technologies, (3) therapeutic innovations, and (4) epidemiological trends. The United States and Yonsei University were the leading contributors in terms of publication and citation counts. Ocular Surface, Cornea, and Investigative Ophthalmology & Visual Science were the top journals by productivity and impact. The study revealed significant progress in MGD research and highlighted key areas requiring further investigation, including the establishment of global diagnostic standards and targeted therapies in regenerative medicine. These findings provide a roadmap for future collaborative efforts and strategic research directions in regenerative medicine of the field.

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Liu, Q., Zhao, F., Liu, J., Guo, M., Jiang, C., Yu, T., Wang, T., Sung, T.-C., Kong, J., & Higuchi, A. (2025). Global Research Trends and Hotspots in Meibomian Gland Dysfunction (2014–2023): A Comprehensive Bibliometric and Visualization Analysis. Regenerative Medicine and Dentistry, 2(1), 4. https://doi.org/10.53941/rmd.2025.100004
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