Articles

Articles

Regenerative Medicine and Dentistry

Open AccessArticle

TNFSF11 as a Key Regulator in Osteoarthritis Pathogenesis: Integrated Bioinformatics Analysis and Potential Therapeutic Targets

Fumin Yuan, Xiwei Fan, Indira Prasadam, Antonia Rujia Sun, Xiaoxin Wu, Yanping Wang, Xinzhan Mao

2026, 3(1): 4. doi: 10.53941/rmd.2026.100004

1 Downloaded

16 Viewed

Open AccessReview

AI-Enabled Dental Care

Chunyu Yang, Long Bai, Jiacan Su

2026, 3(1): 3. doi: 10.53941/rmd.2026.100003

14 Downloaded

54 Viewed

Open AccessReview

mTOR Signalling in Diabetic Peripheral Neuropathy: Balancing Neuropathic Pain and Schwann Cell-Mediated Repair

Ka Huen Cheng, John Akrofi Kubi, Augustine Suurinobah Brah, Mireku Yaw Asante, Yizhou Zhu, Kelvin Wai Kwok Yeung

2026, 3(1): 2. doi: 10.53941/rmd.2026.100002

19 Downloaded

87 Viewed

Open AccessPerspective

From Biomimetic to Bioadaptive: Next-Generation Titanium Implants for Functional Bone Regeneration

Yuanyuan Liu, Dacheng Sang, Yuling Zhang, Chongbin Wei, Feifei Zhou, Zhaojun Jia

2026, 3(1): 1. doi: 10.53941/rmd.2026.100001

34 Downloaded

185 Viewed

Open AccessReview

Overview of Representative Clinical Trials Using Human Pluripotent Stem Cell-Differentiated Cells

Akon Higuchi, Ting Wang, Xin Kang, Zeyu Tian, Tzu-Cheng Sung

2025, 2(4): 20. doi: 10.53941/rmd.2025.100020

58 Downloaded

183 Viewed

Open AccessPerspective

Neutrophil Polarization and Immune Regulation: Toward Immune-Bioadaptive Dental Implants

Jielin Zhou, Fusong Yuan, Zhaojun Jia

2025, 2(4): 19. doi: 10.53941/rmd.2025.100019

42 Downloaded

130 Viewed

Open AccessReview

Biomaterials for Dental Pulp Regeneration: Recent Advances, Mechanistic Insights, and Translational Perspectives

Shijie Gao, Ju Wang, Yuqiang Jiang, Bingrui Chen, Yi Liu, Shengyuan Gao, Yuhan Zhao, Bin Li, Song Chen

2025, 2(4): 18. doi: 10.53941/rmd.2025.100018

100 Downloaded

338 Viewed

Open AccessArticle

Unraveling the Underlying Comorbidity Mechanisms of Atopic Dermatitis and Periodontitis via Bioinformatics

Kaiye Lin, Lv Xie, Guangqi Gao, Yingye Zhang, Na Li, Chunxiao Lv, Zetao Chen

2025, 2(4): 17. doi: 10.53941/rmd.2025.100017

72 Downloaded

206 Viewed

Open AccessReview

Nanomaterials in Oral Regeneration: Current Advances and Future Directions

Songbai Xu, Peiyi Liang, Lili Zhong, Xiying Fu, Yan Li, Yicun Wang

2025, 2(4): 16. doi: 10.53941/rmd.2025.100016

70 Downloaded

268 Viewed

Open AccessArticle

Photo-Curable GelMA-Chitosan Bioadhesive Hydrogel: An Evaluation of Mechanical and Adhesive Properties

Sattwikesh Paul, Karsten Schrobback, Phong Anh Tran, Christoph Meinert, Angus Weekes, Jordan William Davern, Travis Jacob Klein

2025, 2(3): 15. doi: 10.53941/rmd.2025.100015

97 Downloaded

306 Viewed

Open AccessReview

Organoids in Dentistry and Oral Medicine: From Disease Models to Regenerative Medicine

Shangyan Li, Hang Ruan, Jiqing Huang, Linyuan Yu, Boyang Zhang, Ruijia Chen, Kecheng Chen, Lan Yang, Janak Lal Pathak, Qing Zhang

2025, 2(3): 14. doi: 10.53941/rmd.2025.100014

89 Downloaded

338 Viewed

Open AccessArticle

Controlled Codelivery of Hydrogen Sulfide and Nitric Oxide for the Treatment of Full-Thickness Skin Wound

Meng Qian, Guangbo Ji, Pei Liu, Yating Zhang, Weiliang Deng, Zhixin Xu, Huan Wang, Jiansong Cheng, Qiang Zhao

2025, 2(3): 13. doi: 10.53941/rmd.2025.100013

70 Downloaded

161 Viewed

Open AccessArticle

Shared Cell Death and Immune Pathways Link Periodontitis and Rheumatoid Arthritis

Haokun He, Shuaifei Pan, Ling Chen, Siwen Xiao, Shuguang Cheng, Lian Huang, Qing Zhang, Janak L. Pathak

2025, 2(3): 12. doi: 10.53941/rmd.2025.100012

49 Downloaded

139 Viewed

Open AccessArticle

Substrate-Independent Antibacterial Coatings with Optimal Concentration of Covalently Immobilised Silver Nanoparticles That Support Osteogenesis

Neethu Ninan, Fei Wei, Dennis Palms, Peter Zilm, Yunpeng Zhao, Richard Bright, Yin Xiao, Krasimir Vasilev

2025, 2(3): 11. doi: 10.53941/rmd.2025.100011

55 Downloaded

162 Viewed

Open AccessPerspective

Rethinking Osteonecrosis of the Jaw: Could Cellular Senescence Be the Missing Link Between ORN and MRONJ?

Jiahe Zhao, Yige Liu, Jiyuan Liu, Xiufa Tang, Chunjie Li, Zhiyong Guo

2025, 2(3): 10. doi: 10.53941/rmd.2025.100010

66 Downloaded

175 Viewed

Open AccessReview

Therapeutics-Loaded Electrospun Nanofibers: Rational Design and Mechanistic Insights on Managing Chronic Wound Infection

Zakia Riaz, Yu Xuan Fong, Yunn Yee Chan, Tristen Lee, Vincent Chan, Neethu Ninan, Vi Khanh Truong

2025, 2(2): 9. doi: 10.53941/rmd.2025.100009

116 Downloaded

347 Viewed

Open AccessArticle

Graphene Oxide/Chitosan/Calcium Silicate Aerogels for Hemostasis and Infectious Wound Healing

Jianmin Xue, Yi Zheng, Zhibo Yang, Jinzhou Huang, Wenping Ma, Zhiguang Huan, Yufang Zhu, Chengtie Wu

2025, 2(2): 8. doi: 10.53941/rmd.2025.100008

108 Downloaded

238 Viewed

Open AccessReview

Natural Materials in Regenerative Orthopaedics: A Historical Perspective

Olivia Vasilev, David Campbell, Ruurd L. Jaarsma

2025, 2(2): 7. doi: 10.53941/rmd.2025.100007

79 Downloaded

222 Viewed

Open AccessReview

The Current State and Future of Oral Health: A Position Paper Exploring the Role of Regenerative Dentistry

John A. Jansen

2025, 2(1): 6. doi: 10.53941/rmd.2025.100006

91 Downloaded

225 Viewed

Open AccessPerspective

hiPSC-Driven Organoid Construction and Application Prospects

Bangheng Liu, Yulei Mu, Dong-An Wang

2025, 2(1): 5. doi: 10.53941/rmd.2025.100005

79 Downloaded

220 Viewed

1 Cited

Open AccessReview

Global Research Trends and Hotspots in Meibomian Gland Dysfunction (2014–2023): A Comprehensive Bibliometric and Visualization Analysis

Qian Liu, Fangkun Zhao, Jun Liu, Minmei Guo, Chengyu Jiang, Tao Yu, Ting Wang, Tzu-Cheng Sung, Jun Kong, Akon Higuchi

2025, 2(1): 4. doi: 10.53941/rmd.2025.100004

41 Downloaded

142 Viewed

Open AccessPerspective

Underestimated Roles of Osteocytes in Medication-Related Osteonecrosis of the Jaw

Chunfeng Xu, Yiqun Wu

2025, 2(1): 3. doi: 10.53941/rmd.2025.100003

74 Downloaded

161 Viewed

Open AccessArticle

A Novel Missense Mutation at EDA2R Gene Identified in a Case Study Associated with Hypohidrotic Ectodermal Dysplasia

Wan Yang, Siyu Jin, Jie Jiang, Wei Ji, Qing He

2025, 2(1): 2. doi: 10.53941/rmd.2025.100002

63 Downloaded

166 Viewed

Open AccessReview

Insights into Bioengineering Approaches for Aging Bone Regeneration: Strategies to Target Osteoimmunosenescence

Lan Xiao, Wendong Gao, Jinfu Wu, Itsasne Erezuma, Alireza Dolatshahi-Pirouz, Joana Silva-Correia, Yinghong Zhou, Antonia Rujia Sun, Indira Prasadam, Ross Crawford, Joaquim Miguel Oliveira, Gorka Orive, Chengtie Wu, Yin Xiao

2025, 2(1): 1. doi: 10.53941/rmd.2025.100001

78 Downloaded

232 Viewed

Open AccessReview

Impaired Osteoclastogenesis in Medication-Related Osteonecrosis and Potential Clinical Management with BMP-2

Chunfeng Xu, Yin Xiao, Yiqun Wu, Astrid Bakker, Yuelian Liu

2024, 1(1): 5. doi: 10.53941/rmd.2024.100005

47 Downloaded

186 Viewed

1 Cited

Open AccessReview

Cell Secretome from Mesenchymal Stem Cells for Periodontal Regeneration

Bin Chen, Lili Li, Xiaoxin Zhang, Qing Liu, Yin Xiao, Fuhua Yan

2024, 1(1): 4. doi: 10.53941/rmd.2024.100004

74 Downloaded

211 Viewed

Open AccessReview

Application of Saccharide Cryoprotectants in the Freezing or Lyophilization Process of Lipid Nanoparticles Encapsulating Gene Drugs for Regenerative Medicine

Wanqi Li, Ting Wang, Jianyang Chen, Minmei Guo, Ling Ling, Akon Higuchi

2024, 1(1): 3. doi: 10.53941/rmd.2024.100003

132 Downloaded

394 Viewed

5 Cited

Open AccessArticle

Intravenous Transplantation of Apoptosis Repressor with Caspase Recruitment Domain-Overexpressing Mesenchymal Stem Cells Promotes Bone Formation in Bisphosphonate-Related Osteonecrosis of the Jaw Rats

Ruixue Jiang, Yuwei Deng, Yuhui Zhu, Jin Wen, Xinquan Jiang, Longwei Hu

2024, 1(1): 2. doi: 10.53941/rmd.2024.100002

34 Downloaded

101 Viewed

Open AccessEditorial

Regenerative Medicine and Dentistry

Yin Xiao, Krasimir Vasilev, Yuelian Liu, Akon Higuchi

2024, 1(1): 1. doi: 10.53941/rmd.2024.100001

31 Downloaded

145 Viewed