Open Access
Review
Coronary Microvascular Dysfunction: A Potential Intervention Strategy against Acute Myocardial Infarction
Zihan Wang1
, Lianhua Fang1
, Yang Lv2
, Shoubao Wang1, *
, Guanhua Du1, *
Author Information
Submitted: 26 Aug 2024 | Revised: 11 Oct 2024 | Accepted: 11 Oct 2024 | Published: 14 Feb 2025
Abstract
Recent studies have illuminated the role of coronary microvascular dysfunction (CMD) as a pivotal contributor to acute myocardial infarction (AMI). Microvascular dysfunction may lead to severe results including microvascular obstruction (MVO) and intramyocardial hemorrhage (IMH), which are associated with poor prognosis. This article reviews the current research on coronary microvascular dysfunction in myocardial infarction reperfusion including the mechanisms, methods and models assessing CMD. This review emphasizes the importance of CMD and proposes potential avenues for future research in this field. Interventions for CMD may pave the way for novel treatment strategies in the management of acute myocardial infarction (AMI).
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Volume 4, Issue 1How to Cite
Wang, Z., Fang, L., Lv, Y., Wang, S., & Du, G. (2025). Coronary Microvascular Dysfunction: A Potential Intervention Strategy against Acute Myocardial Infarction. International Journal of Drug Discovery and Pharmacology, 4(1), 100004. https://doi.org/10.53941/ijddp.2025.100004
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