Scilight Press

The antimicrobial activity of Tinospora cordifolia aqueous extract was screened against gram-positive and negative multiple drug-resistant (MDR) bacterial strains. Gram-positive included Bacillus cereus, Bacillus paranthracis and gram-negative included Aeromonas hydrophila, Aeromonas caviae and Aeromonas dhakensis. These strains were isolated from wastewater treatment plants having domestic and hospital discharge and conferred resistance against most frequently used antibiotics. These multiple drug resistance bacterial strains showed sensitivity towards aqueous extract of T. cordifolia. The present study concluded that all selected bacterial strains showed a 17.9 mm lowest zone of inhibition and 33.9 mm highest in the case of gram-positive bacteria. Similarly, in the case of gram-negative bacteria, the lowest of 19 mm and the highest of 32.5 mm zone of inhibition.