Autistic people, as is the case with many health conditions, are subject to stigmatization. We aim to ameliorate this situation and increase positive attitudes toward autistic people. Grounded in the imagined contact hypothesis, we investigated the effect of imagined musical interaction with an autistic person on non-autistic people’s attitudes toward autistic people in general. We conducted an online experiment in which non-autistic college students (N = 443) were randomly assigned to 2 (music vs. non-musical) × 2 (autistic student vs. non-autistic student) conditions. Thus, participants imagined communicating with an autistic (or non-autistic) peer student while doing a music-related (or math-related) school activity. Imagining musical (vs. non-musical) interactions with an autistic person marginally significantly increased a sense of synchronization with the target, which then contributed to reduced social distance. Results were discussed in relation to the imagined contact hypothesis and the broader applicability of music to reduce stigma.