Translational Insights
Editor-in-Chief: Prof. Francesco M. Marincola, TAM Biosciences, USA; TAM Global, USA.
Translational Insights (TI) is a peer-reviewed biomedical publication dedicated to fostering, expediting, and streamlining the conversion of basic and preclinical discoveries into the seamless delivery of useful therapeutics for the improvement of human health. TI is a broad-reaching journal covering all areas of medical research spanning from biomedical discoveries to clinical applications, exploiting advanced bioinformatics tools such as artificial intelligence and machine learning for target and biomarker discovery. Moreover, TI welcomes innovative epidemiological surveys, assessments of policies and processes relevant to the biomedical ecosystem that identify hurdles to efficient clinical testing of promising therapeutics and define strategies to overcome them. TI welcomes submissions within this scope, prioritizing impactful discoveries and providing speedy editorial decisions. More
- Open AccessArticle
Molecular Mimicry in the Dark Immunopeptidome: Viral-Homologous Non-Canonical Tumor Peptides as Targets for Off-the-Shelf Cancer Vaccines
Angela Mauriello, Beatrice Cavalluzzo, Concetta Ragone, Biancamaria Cembrola, Simona Mangano, Luigi Buonaguro, Maria Tagliamonte
2026, 1(1): 14. doi: 10.53941/ti.2026.100014
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Efficient Adaptation of Chemical Language Models for Molecular Property Prediction
Kavya Agrawal, Harsha Harod, Ines Simeone, Michele Ceccarelli, Halima Bensmail, Sukrit Gupta, Raghvendra Mall
2026, 1(1): 13. doi: 10.53941/ti.2026.100013
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- Open AccessReview
From Public Health to Precision Nutrition: Convergences and Divergences Between the U.S. Dietary Guidelines and the Chronobiology-Based Mediterranean Diet
Giuseppe Annunziata, Ludovica Verde, Martina Galasso, Giovanna Muscogiuri, Luigi Barrea
2026, 1(1): 12. doi: 10.53941/ti.2026.100012
Download PDF18 Downloaded60 Viewed - Open AccessArticle
Cognition-Weighted Multimodal MRI and FDG-PET Features for Classification of Mild Cognitive Impairment, Alzheimer’s Disease, and Frontotemporal Dementia
Sunil Kumar Khokhar, Rohit Misra, Manoj Kumar, Faheem Arshad, Nithin Thanissery, Sandeep Kumar, Tejaswini Manae, Subasree Ramakrishnan, Mohammad Haris, Sandhya Mangalore, Suvarna Alladi, Tapan Kumar Gandhi, Rose Dawn Bharath
2026, 1(1): 11. doi: 10.53941/ti.2026.100011
Download PDF32 Downloaded87 Viewed - Open AccessReview
Mitochondrial DNA and Mitochondrial-Derived Vesicles as Immunometabolic Modulators of Innate Immunosurveillance through Control of the Mitochondrial Permeability Transition Pore
Salvatore Nesci, Patrycja Anna Glogowski, Antonia Cugliari, Fabiana Trombetti, Micaela Fabbri, Cristina Algieri
2026, 1(1): 10. doi: 10.53941/ti.2026.100010
Download PDF6 Downloaded34 Viewed - Open AccessCommentary
A First-Principles Framework for Accelerating Translational Medicine
Edward Clay, Annette Marleau
2026, 1(1): 9. doi: 10.53941/ti.2026.100009
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Macrophages in Lymphoma: Advances in Biology and Treatment
Mengya Gao, Siyue Li, Linping Xu, Shiyu Zuo, Wei Li
2026, 1(1): 8. doi: 10.53941/ti.2026.100008
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Mitochondrial Complex IV in Free form Controls Respiratory Channeling Independently of Supercomplex Assembly
Patrycja Anna Glogowski, Cristina Algieri, Antonia Cugliari, Maria Cotugno, Donatella Pietrangelo, Fabiana Trombetti, Micaela Fabbri, Speranza Rubattu, Salvatore Nesci
2026, 1(1): 7. doi: 10.53941/ti.2026.100007
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Dissecting the Transcriptional Variability of Breast Cancer-Associated Fibroblasts Using Different Culture Conditions
Marianna Talia, Francesca Cirillo, Domenica Scordamaglia, Azzurra Zicarelli, Marika Di Dio, Adelina Assunta Mondino, Francesca Silvestri, Chiara Meliti, Ernestina Marianna De Francesco, Roberta Malaguarnera, Anna Maria Miglietta, Marcello Maggiolini, Rosamaria Lappano
2026, 1(1): 6. doi: 10.53941/ti.2026.100006
Download PDF41 Downloaded174 Viewed - Open AccessArticle
Ascorbate in Pharmacological Concentrations Potentiates the Anti-Tumor Activity of NK and CD8+ T Cells and Synergizes with Chemotherapy for Enhanced Anti-Tumor Immune Response against 3D Breast Cancer Spheroid Models
Ali Mussa, Mahasin Hamid, Ahmad Hafiz Murtadha, Mustafa Talib, Khalid Hajisa, Noor Fatmawati Mokhtar, Rohimah Mohamud, Mohammad AI Al-Hatamleh, Rosline Hassan
2026, 1(1): 5. doi: 10.53941/ti.2026.100005
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