Articles

Articles

Open AccessReview

Expanding Access to Cell and Gene Therapies

David Stroncek, Anh Dinh, Jiaqiang Ren

2026, 1(1): 26. doi: 10.53941/ti.2026.100026

5 Downloaded
26 Viewed
Download PDF
Open AccessReview

Is Neuroblastoma A Case of Viral Mimicry Suppression?

Ugo Rovigatti

2026, 1(1): 24. doi: 10.53941/ti.2026.100024

5 Downloaded
33 Viewed
Download PDF
Open AccessArticle

HEK293T Vesicle Lipidomes Retain Core Features of Their Parent Cells

Kyle Peres, Krishna Kishor, Sanjoy K. Bhattacharya

2026, 1(1): 23. doi: 10.53941/ti.2026.100023

59 Downloaded
302 Viewed
Download PDF
Open AccessArticle

A Humanized HLA-Matched Avatar Model for Preclinical Evaluation of DNA Cancer Vaccines

Erika Salvatori, Lucia Lione, Melanie Paccagnella, Eleonora Pinto, Mariantonina Greco, Emanuele Marra, Giuseppe Roscilli, Gennaro Ciliberto, Luigi Aurisicchio, Antonella Conforti

2026, 1(1): 22. doi: 10.53941/ti.2026.100022

16 Downloaded
105 Viewed
Download PDF
Open AccessStudy Protocol

The FraiLtx Study Protocol: A Prospective, Single-Center Observational Study on Frailty, Systemic Inflammation, and Monocyte Subsets in Liver Transplant Candidates

Ole Sattler, Anja Bosy-Westphal, Gunnar Elke, Amke Caliebe, Christian Peters, Karina Silvana Zitta, Martin Albrecht, Felix Braun, Anna Lulu Homayr

2026, 1(1): 20. doi: 10.53941/ti.2026.100020

14 Downloaded
52 Viewed
Download PDF
Open AccessReview

In Vivo CAR-T Cell Engineering: Translating Vector Pharmacology into Therapeutic Performance

Jiaqiang Ren, David Stroncek, Anh Dinh

2026, 1(1): 19. doi: 10.53941/ti.2026.100019

32 Downloaded
201 Viewed
Download PDF
Open AccessArticle

Association of Antibiotic Exposure with Survival Outcomes in Patients with Advanced KRAS-Mutated NSCLC Receiving Immune Checkpoint Inhibitors

Qianlin Huang, Weichi Luo, Yichen Zhang, Zhihong Chen, Qiuyi Zhang, Fen Wang, Jianhua Chang, Qing Zhou

2026, 1(1): 16. doi: 10.53941/ti.2026.100016

19 Downloaded
82 Viewed
Download PDF
Open AccessArticle

PPE-Associated Skin Lesions Among ICU Healthcare Workers: Clinical Characteristics and Anatomical Distribution

Anahita Akbari, Amir Hossein Siadat, Zahra mollabashi, Sayed Mohsen Hosseini, Fariba Iraji

2026, 1(1): 15. doi: 10.53941/ti.2026.100015

15 Downloaded
100 Viewed
Download PDF
Open AccessArticle

Molecular Mimicry in the Dark Immunopeptidome: Viral-Homologous Non-Canonical Tumor Peptides as Targets for Off-the-Shelf Cancer Vaccines

Angela Mauriello, Beatrice Cavalluzzo, Concetta Ragone, Biancamaria Cembrola, Simona Mangano, Luigi Buonaguro, Maria Tagliamonte

2026, 1(1): 14. doi: 10.53941/ti.2026.100014

41 Downloaded
242 Viewed
Download PDF
Open AccessArticle

Efficient Adaptation of Chemical Language Models for Molecular Property Prediction

Kavya Agrawal, Harsha Harod, Ines Simeone, Michele Ceccarelli, Halima Bensmail, Sukrit Gupta, Raghvendra Mall

2026, 1(1): 13. doi: 10.53941/ti.2026.100013

23 Downloaded
154 Viewed
Download PDF
Open AccessReview

From Public Health to Precision Nutrition: Convergences and Divergences Between the U.S. Dietary Guidelines and the Chronobiology-Based Mediterranean Diet

Giuseppe Annunziata, Ludovica Verde, Martina Galasso, Giovanna Muscogiuri, Luigi Barrea

2026, 1(1): 12. doi: 10.53941/ti.2026.100012

29 Downloaded
125 Viewed
Download PDF
Open AccessArticle

Cognition-Weighted Multimodal MRI and FDG-PET Features for Classification of Mild Cognitive Impairment, Alzheimer’s Disease, and Frontotemporal Dementia

Sunil Kumar Khokhar, Rohit Misra, Manoj Kumar, Faheem Arshad, Nithin Thanissery, Sandeep Kumar, Tejaswini Manae, Subasree Ramakrishnan, Mohammad Haris, Sandhya Mangalore, Suvarna Alladi, Tapan Kumar Gandhi, Rose Dawn Bharath

2026, 1(1): 11. doi: 10.53941/ti.2026.100011

39 Downloaded
170 Viewed
Download PDF
Open AccessReview

Mitochondrial DNA and Mitochondrial-Derived Vesicles as Immunometabolic Modulators of Innate Immunosurveillance through Control of the Mitochondrial Permeability Transition Pore

Salvatore Nesci, Patrycja Anna Glogowski, Antonia Cugliari, Fabiana Trombetti, Micaela Fabbri, Cristina Algieri

2026, 1(1): 10. doi: 10.53941/ti.2026.100010

17 Downloaded
134 Viewed
Download PDF
Open AccessCommentary

A First-Principles Framework for Accelerating Translational Medicine

Edward Clay, Annette Marleau

2026, 1(1): 9. doi: 10.53941/ti.2026.100009

47 Downloaded
254 Viewed
Download PDF
Open AccessReview

Macrophages in Lymphoma: Advances in Biology and Treatment

Mengya Gao, Siyue Li, Linping Xu, Shiyu Zuo, Wei Li

2026, 1(1): 8. doi: 10.53941/ti.2026.100008

42 Downloaded
167 Viewed
Download PDF
Open AccessArticle

Mitochondrial Complex IV in Free form Controls Respiratory Channeling Independently of Supercomplex Assembly

Patrycja Anna Glogowski, Cristina Algieri, Antonia Cugliari, Maria Cotugno, Donatella Pietrangelo, Fabiana Trombetti, Micaela Fabbri, Speranza Rubattu, Salvatore Nesci

2026, 1(1): 7. doi: 10.53941/ti.2026.100007

35 Downloaded
133 Viewed
Download PDF
Open AccessArticle

Dissecting the Transcriptional Variability of Breast Cancer-Associated Fibroblasts Using Different Culture Conditions

Marianna Talia, Francesca Cirillo, Domenica Scordamaglia, Azzurra Zicarelli, Marika Di Dio, Adelina Assunta Mondino, Francesca Silvestri, Chiara Meliti, Ernestina Marianna De Francesco, Roberta Malaguarnera, Anna Maria Miglietta, Marcello Maggiolini, Rosamaria Lappano

2026, 1(1): 6. doi: 10.53941/ti.2026.100006

54 Downloaded
239 Viewed
Download PDF
Open AccessArticle

Ascorbate in Pharmacological Concentrations Potentiates the Anti-Tumor Activity of NK and CD8+ T Cells and Synergizes with Chemotherapy for Enhanced Anti-Tumor Immune Response against 3D Breast Cancer Spheroid Models

Ali Mussa, Mahasin Hamid, Ahmad Hafiz Murtadha, Mustafa Talib, Khalid Hajisa, Noor Fatmawati Mokhtar, Rohimah Mohamud, Mohammad AI Al-Hatamleh, Rosline Hassan

2026, 1(1): 5. doi: 10.53941/ti.2026.100005

80 Downloaded
434 Viewed
Download PDF
Open AccessArticle

A Novel Multiplex Immunoassay for the Early Detection of Bladder Cancer: Study Protocol for a Prospective, Observational Cohort Study

Greg Gin, Michael Luu, Hideki Furuya, Charles J. Rosser

2026, 1(1): 4. doi: 10.53941/ti.2026.100004

23 Downloaded
115 Viewed
Download PDF
Open AccessReview

The Perfect Storm: Viral Mimicry Meets Cancer Dark Matter

Joyce Hu, Francesco M. Marincola, Edward Clay, Erik Hett

2026, 1(1): 3. doi: 10.53941/ti.2026.100003

93 Downloaded
354 Viewed
Download PDF
Open AccessReview

Factors Affecting the Potency and Safety of Chimeric Antigen Receptor T-Cells

David F. Stroncek, Lipei Shao, Ping Jin

2026, 1(1): 2. doi: 10.53941/ti.2026.100002

38 Downloaded
169 Viewed
Download PDF
Open AccessEditorial

Translational Insights: A Paradigm Reversal in Translational Research

Yang Liang, Francesco M. Marincola

2026, 1(1): 1. doi: 10.53941/ti.2026.100001

61 Downloaded
276 Viewed
Download PDF