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Open AccessArticle

Unraveling the Mechanism of Higenamine in the Treatment of Right Heart Failure via Computational Drug Discovery and Molecular Simulation Technology

Yujie Qu, Yinghua Huo, Yichen Wang, Xue Yu, Leiyu Tian, Jian Guo, Ling Chen, Yucai Chen

2026, 5(3): 100018. doi: 10.53941/ijddp.2026.100018

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Open AccessReview

Myocardial Lipotoxicity in Cardiovascular Diseases: Mechanisms, Therapeutic Strategies, and Drug Target Discovery

Yaxin Xu, Xinrui Li, Lu Fu

2026, 5(2): 100009. doi: 10.53941/ijddp.2026.100009

34 Downloaded
270 Viewed
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Open AccessReview

Exploring Pathological Mechanisms and Pharmacological Interventions in Acute Myocardial Infarction and Acute Heart Failure

Gaurang Shah, Anil Kumar Prajapati

2025, 4(4): 100021. doi: 10.53941/ijddp.2025.100021

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379 Viewed
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Open AccessReview

Alkaloids and Their Mechanisms of Action in Cardiovascular Diseases

Anil Kumar Prajapati, Gaurang Shah

2025, 4(3): 100017. doi: 10.53941/ijddp.2025.100017

71 Downloaded
495 Viewed
1 Cited
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Open AccessReview

The Underestimated Diabetic Cardiomyopathy: Its Role in Heart Failure Progression and Implications for Drug Discovery

Felycia Fernanda Hosyanto, Jiang Min, Suxin Luo, Shenglan Yang

2025, 4(3): 100015. doi: 10.53941/ijddp.2025.100015

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Open AccessCommunication
Strategizing Cardiovascular Management in Diabetic Patients: Insights and Advancements from the 2023 ESC Guidelines for the Management of Cardiovascular Disease in Patients with Diabetes

Hongyuan Zhang, Darren Green, Yanrong Liu

2025, 4(1): 100002. doi: 10.53941/ijddp.2025.100002

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Open AccessReview
Transverse Tubules in Cardiac Health and Disease: Therapeutic Approaches to T-Tubule Remodelling and Heart Failure Management

Vanya Kalyan

2024, 3(4): 100024. doi: 10.53941/ijddp.2024.100024

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Open AccessReview
Inhibiting the Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Cascade in Cancer and the Heart: for Better or Worse, in Sickness and Health?

Angela Clerk, Shona U Amadi, Samuel J Smith, Peter H Sugden

2024, 3(2): 100006. doi: 10.53941/ijddp.2024.100006

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1 Cited
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Open AccessReview
Breaking Boundaries: Novel Effects of Levosimendan in Various Diseases

Hongyuan Zhang, Minxing Zhao, Yanrong Liu

2024, 3(1): 100005. doi: 10.53941/ijddp.2024.100005

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Open AccessArticle
Mkk7 Protects Against Cardiac Dysfunction in Heart Failure with Preserved Ejection Fraction

Tayyiba Azam, Hongyuan Zhang, Susanne Hille, Oliver J. Müller, Elizabeth J. Cartwright, Xin Wang

2024, 3(1): 100002. doi: 10.53941/ijddp.2024.100002

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Open AccessArticle
Overexpressing Mitogen-activated Protein Kinase Kinase 7 (MKK7) Alleviates Endoplasmic Reticulum Stress-induced Cardiac Dysfunction during Pressure Overload induced Heart Failure

Tayyiba Azam, Min Zi, Susanne S. Hille, Hongyuan Zhang, Elizabeth J. Cartwright, Oliver J. Müller, Xin Wang

2023, 2(4): 23-35. doi: 10.53941/ijddp.2023.100013

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Open AccessReview
Effect of Glucagon-like Peptide-1 Receptor Agonist on Cardiac Structure and Function in Patients with Heart Failure: A Systematic Review and Meta-analysis

Xinyu Zhang, Hongyuan Zhang

2023, 2(3): 117-129. doi: 10.53941/ijddp.2023.100010

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Open AccessReview
Is miR-21 A Therapeutic Target in Cardiovascular Disease?

Antoinette Holland, Molly Enrick, Arianna Diaz, Liya Yin

2023, 2(1): 26-36. doi: 10.53941/ijddp.0201003

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22 Cited
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Open AccessReview
Cardiac β-Adrenoceptor Signaling: The New Insight on An Old Target in the Therapy of Cardiovascular Disease

Ying Song, Anthony Yiu-Ho WOO, Yan Zhang, Ruiping Xiao

2022, 1(1): 3. doi: 10.53941/ijddp.v1i1.177

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