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Open AccessArticle

Unraveling the Mechanism of Higenamine in the Treatment of Right Heart Failure via Computational Drug Discovery and Molecular Simulation Technology

Yujie Qu, Yinghua Huo, Yichen Wang, Xue Yu, Leiyu Tian, Jian Guo, Ling Chen, Yucai Chen

2026, 5(3): 100018. doi: 10.53941/ijddp.2026.100018

11 Downloaded
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Open AccessReview

Myocardial Lipotoxicity in Cardiovascular Diseases: Mechanisms, Therapeutic Strategies, and Drug Target Discovery

Yaxin Xu, Xinrui Li, Lu Fu

2026, 5(2): 100009. doi: 10.53941/ijddp.2026.100009

39 Downloaded
376 Viewed
1 Cited
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Open AccessReview

Macrophage Metabolic Reprogramming and Its Role in Heart Diseases

Xingkai Huang, Gangjie Zhu, Shenghang Liu, Yigang Zhong, Hanwen Zhang

2026, 5(1): 100006. doi: 10.53941/ijddp.2026.100006

39 Downloaded
325 Viewed
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Open AccessReview

Exploring Pathological Mechanisms and Pharmacological Interventions in Acute Myocardial Infarction and Acute Heart Failure

Gaurang Shah, Anil Kumar Prajapati

2025, 4(4): 100021. doi: 10.53941/ijddp.2025.100021

70 Downloaded
429 Viewed
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Open AccessReview

Alkaloids and Their Mechanisms of Action in Cardiovascular Diseases

Anil Kumar Prajapati, Gaurang Shah

2025, 4(3): 100017. doi: 10.53941/ijddp.2025.100017

79 Downloaded
533 Viewed
3 Cited
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Open AccessReview

The Underestimated Diabetic Cardiomyopathy: Its Role in Heart Failure Progression and Implications for Drug Discovery

Felycia Fernanda Hosyanto, Jiang Min, Suxin Luo, Shenglan Yang

2025, 4(3): 100015. doi: 10.53941/ijddp.2025.100015

42 Downloaded
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Open AccessCommunication
Strategizing Cardiovascular Management in Diabetic Patients: Insights and Advancements from the 2023 ESC Guidelines for the Management of Cardiovascular Disease in Patients with Diabetes

Hongyuan Zhang, Darren Green, Yanrong Liu

2025, 4(1): 100002. doi: 10.53941/ijddp.2025.100002

41 Downloaded
293 Viewed
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Open AccessReview
Modeling Arrhythmia in a Dish: An Open View from Human-Engineered Heart Constructs

Shiya Wang, Pengcheng Yang, Jonathan Nimal Selvaraj, Donghui Zhang

2025, 4(1): 100001. doi: 10.53941/ijddp.2025.100001

48 Downloaded
599 Viewed
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Open AccessReview
Transverse Tubules in Cardiac Health and Disease: Therapeutic Approaches to T-Tubule Remodelling and Heart Failure Management

Vanya Kalyan

2024, 3(4): 100024. doi: 10.53941/ijddp.2024.100024

29 Downloaded
192 Viewed
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Open AccessReview
The Role of Autophagy in Heart Disease

Osman Mohiuddin, Sabu Abraham, Hongyuan Zhang, Andrea Ruiz-Velasco

2024, 3(4): 100021. doi: 10.53941/ijddp.2024.100021

25 Downloaded
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1 Cited
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Open AccessReview
Inhibiting the Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Cascade in Cancer and the Heart: for Better or Worse, in Sickness and Health?

Angela Clerk, Shona U Amadi, Samuel J Smith, Peter H Sugden

2024, 3(2): 100006. doi: 10.53941/ijddp.2024.100006

24 Downloaded
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2 Cited
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Open AccessReview
Breaking Boundaries: Novel Effects of Levosimendan in Various Diseases

Hongyuan Zhang, Minxing Zhao, Yanrong Liu

2024, 3(1): 100005. doi: 10.53941/ijddp.2024.100005

29 Downloaded
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Open AccessArticle
Mkk7 Protects Against Cardiac Dysfunction in Heart Failure with Preserved Ejection Fraction

Tayyiba Azam, Hongyuan Zhang, Susanne Hille, Oliver J. Müller, Elizabeth J. Cartwright, Xin Wang

2024, 3(1): 100002. doi: 10.53941/ijddp.2024.100002

31 Downloaded
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1 Cited
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Open AccessArticle
Overexpressing Mitogen-activated Protein Kinase Kinase 7 (MKK7) Alleviates Endoplasmic Reticulum Stress-induced Cardiac Dysfunction during Pressure Overload induced Heart Failure

Tayyiba Azam, Min Zi, Susanne S. Hille, Hongyuan Zhang, Elizabeth J. Cartwright, Oliver J. Müller, Xin Wang

2023, 2(4): 23-35. doi: 10.53941/ijddp.2023.100013

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Open AccessReview
Effect of Glucagon-like Peptide-1 Receptor Agonist on Cardiac Structure and Function in Patients with Heart Failure: A Systematic Review and Meta-analysis

Xinyu Zhang, Hongyuan Zhang

2023, 2(3): 117-129. doi: 10.53941/ijddp.2023.100010

23 Downloaded
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1 Cited
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Open AccessReview
Quantitative Risk Stratification Models for Coronary Heart Disease in Primary and Secondary Prevention

Jia Wei, Qiang Yang, lin Lin, Canzhan Zhu, Jin Wei

2023, 2(3): 87-96. doi: 10.53941/ijddp.2023.100007

24 Downloaded
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Open AccessReview
Is miR-21 A Therapeutic Target in Cardiovascular Disease?

Antoinette Holland, Molly Enrick, Arianna Diaz, Liya Yin

2023, 2(1): 26-36. doi: 10.53941/ijddp.0201003

22 Downloaded
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25 Cited
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Open AccessReview
Cardiac β-Adrenoceptor Signaling: The New Insight on An Old Target in the Therapy of Cardiovascular Disease

Ying Song, Anthony Yiu-Ho WOO, Yan Zhang, Ruiping Xiao

2022, 1(1): 3. doi: 10.53941/ijddp.v1i1.177

40 Downloaded
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7 Cited
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