Articles

Articles

Open AccessArticle

Unraveling the Mechanism of Higenamine in the Treatment of Right Heart Failure via Computational Drug Discovery and Molecular Simulation Technology

Yujie Qu, Yinghua Huo, Yichen Wang, Xue Yu, Leiyu Tian, Jian Guo, Ling Chen, Yucai Chen

2026, 5(3): 100018. doi: 10.53941/ijddp.2026.100018

22 Downloaded
97 Viewed
Download PDF
Open AccessReview

Macrophage Metabolic Reprogramming and Its Role in Heart Diseases

Xingkai Huang, Gangjie Zhu, Shenghang Liu, Yigang Zhong, Hanwen Zhang

2026, 5(1): 100006. doi: 10.53941/ijddp.2026.100006

43 Downloaded
412 Viewed
Download PDF
Open AccessReview

Alkaloids and Their Mechanisms of Action in Cardiovascular Diseases

Anil Kumar Prajapati, Gaurang Shah

2025, 4(3): 100017. doi: 10.53941/ijddp.2025.100017

89 Downloaded
638 Viewed
4 Cited
Download PDF
Open AccessReview

The Underestimated Diabetic Cardiomyopathy: Its Role in Heart Failure Progression and Implications for Drug Discovery

Felycia Fernanda Hosyanto, Jiang Min, Suxin Luo, Shenglan Yang

2025, 4(3): 100015. doi: 10.53941/ijddp.2025.100015

42 Downloaded
264 Viewed
Download PDF
Open AccessReview
Modeling Arrhythmia in a Dish: An Open View from Human-Engineered Heart Constructs

Shiya Wang, Pengcheng Yang, Jonathan Nimal Selvaraj, Donghui Zhang

2025, 4(1): 100001. doi: 10.53941/ijddp.2025.100001

50 Downloaded
623 Viewed
Download PDF
Open AccessReview
The Role of Autophagy in Heart Disease

Osman Mohiuddin, Sabu Abraham, Hongyuan Zhang, Andrea Ruiz-Velasco

2024, 3(4): 100021. doi: 10.53941/ijddp.2024.100021

25 Downloaded
198 Viewed
1 Cited
Download PDF
Open AccessReview
Inhibiting the Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Cascade in Cancer and the Heart: for Better or Worse, in Sickness and Health?

Angela Clerk, Shona U Amadi, Samuel J Smith, Peter H Sugden

2024, 3(2): 100006. doi: 10.53941/ijddp.2024.100006

24 Downloaded
195 Viewed
2 Cited
Download PDF
Open AccessReview
Breaking Boundaries: Novel Effects of Levosimendan in Various Diseases

Hongyuan Zhang, Minxing Zhao, Yanrong Liu

2024, 3(1): 100005. doi: 10.53941/ijddp.2024.100005

30 Downloaded
146 Viewed
1 Cited
Download PDF
Open AccessArticle
Mkk7 Protects Against Cardiac Dysfunction in Heart Failure with Preserved Ejection Fraction

Tayyiba Azam, Hongyuan Zhang, Susanne Hille, Oliver J. Müller, Elizabeth J. Cartwright, Xin Wang

2024, 3(1): 100002. doi: 10.53941/ijddp.2024.100002

32 Downloaded
153 Viewed
1 Cited
Download PDF
Open AccessArticle
Overexpressing Mitogen-activated Protein Kinase Kinase 7 (MKK7) Alleviates Endoplasmic Reticulum Stress-induced Cardiac Dysfunction during Pressure Overload induced Heart Failure

Tayyiba Azam, Min Zi, Susanne S. Hille, Hongyuan Zhang, Elizabeth J. Cartwright, Oliver J. Müller, Xin Wang

2023, 2(4): 23–35. doi: 10.53941/ijddp.2023.100013

17 Downloaded
120 Viewed
Download PDF
Open AccessReview
Quantitative Risk Stratification Models for Coronary Heart Disease in Primary and Secondary Prevention

Jia Wei, Qiang Yang, lin Lin, Canzhan Zhu, Jin Wei

2023, 2(3): 87–96. doi: 10.53941/ijddp.2023.100007

24 Downloaded
178 Viewed
Download PDF
Open AccessReview
Is miR-21 A Therapeutic Target in Cardiovascular Disease?

Antoinette Holland, Molly Enrick, Arianna Diaz, Liya Yin

2023, 2(1): 26–36. doi: 10.53941/ijddp.0201003

23 Downloaded
170 Viewed
29 Cited
Download PDF
Open AccessReview
Cardiac β-Adrenoceptor Signaling: The New Insight on An Old Target in the Therapy of Cardiovascular Disease

Ying Song, Anthony Yiu-Ho WOO, Yan Zhang, Ruiping Xiao

2022, 1(1): 3. doi: 10.53941/ijddp.v1i1.177

43 Downloaded
224 Viewed
7 Cited
Download PDF