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Open AccessReview

Advances and Prospects of Cardiac Organoids in Drug Development

Xiaoying Liu, Yingjuan Liu, Yutong Yan, Fay Pu, Sam Butterworth, Hongyuan Zhang

2026, doi: 10.53941/ijddp.2026.100022

8 Viewed
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Open AccessReview

Dental Erosion and Therapeutic Options

Tangmuqi Jiang, Xuya Kang, Yahan Liu, Yan Zhang

2026, 5(3): 100019. doi: 10.53941/ijddp.2026.100019

12 Downloaded
119 Viewed
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Open AccessArticle

Distinct Sex-Specific Characteristics of Apoe Deficient and Ldlr Deficient Mice in Atherosclerosis: Implications for Model Selection and Therapy Development

Yaping Zhao, Li Wang, Bradford C. Berk, Hans Strijdom, Yu Huang, Jianping Weng, Suowen Xu

2026, 5(3): 100017. doi: 10.53941/ijddp.2026.100017

15 Downloaded
76 Viewed
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Open AccessReview

Myocardial Lipotoxicity in Cardiovascular Diseases: Mechanisms, Therapeutic Strategies, and Drug Target Discovery

Yaxin Xu, Xinrui Li, Lu Fu

2026, 5(2): 100009. doi: 10.53941/ijddp.2026.100009

39 Downloaded
389 Viewed
1 Cited
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Open AccessReview

Rho/ROCK Pathway as a Therapeutic Target in Multiple Diseases

Zixiu Cheng, Shannon Erhardt, Jun Wang

2025, 4(3): 100018. doi: 10.53941/ijddp.2025.100018

132 Downloaded
1088 Viewed
7 Cited
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Open AccessReview

Alkaloids and Their Mechanisms of Action in Cardiovascular Diseases

Anil Kumar Prajapati, Gaurang Shah

2025, 4(3): 100017. doi: 10.53941/ijddp.2025.100017

79 Downloaded
534 Viewed
3 Cited
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Open AccessArticle

The Effects and Mechanism of Guilu Bushen Pill in the Treatment of Osteoporosis Model in Ovariectomized Rats

Ximing Peng, Junjie Huang, Peifang Lai, Xiaorong Zhang, Mingdeng Guan, Xin Hu, Yimeng Ma, Meiqi Ji, Haiyan Gong, Chunhong Li, Xiuping Chen, Huaqian Wang

2025, 4(3): 100016. doi: 10.53941/ijddp.2025.100016

43 Downloaded
601 Viewed
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Open AccessArticle
Analyzing the Structure-Activity Relationship of Necrostain-1 and Its Analogues as RIPK1 Inhibitors on Necroptosis

Huilin Liu, Heng Wang, Haoyi Zheng, Xiuping Chen

2025, 4(2): 100012. doi: 10.53941/ijddp.2025.100012

83 Downloaded
310 Viewed
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Open AccessReview
Exploring Fungi Within the Human Gut Microbiota: Obstacles, Innovations, Therapeutic Applications and Prospects Ahead

Peng Xue, Chao Luo, Jiashu Li, Liang Yang, Yuanyuan Ma

2025, 4(2): 100007. doi: 10.53941/ijddp.2025.100007

57 Downloaded
217 Viewed
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Open AccessReview
Research and Prospects on the Evaluation of Drug Cocrystal Permeability

Shuang Li, Meiru Liu, Dezhi Yang, Li Zhang, Yang Lu, Guanhua Du

2025, 4(1): 100005. doi: 10.53941/ijddp.2025.100005

61 Downloaded
253 Viewed
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Open AccessCommunication
Strategizing Cardiovascular Management in Diabetic Patients: Insights and Advancements from the 2023 ESC Guidelines for the Management of Cardiovascular Disease in Patients with Diabetes

Hongyuan Zhang, Darren Green, Yanrong Liu

2025, 4(1): 100002. doi: 10.53941/ijddp.2025.100002

41 Downloaded
293 Viewed
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Open AccessArticle
Ginsenoside Re Alleviates Oxidative Stress Damage and Ferroptosis in Pulmonary Fibrosis Mice by Regulating the Nrf2/Keap1/GPX4 axis

Huicai Lin, Zhaoqin Wen, Linying Feng, Xiaoyan Chen, Yongxiang Song, Jiang Deng

2024, 3(4): 100025. doi: 10.53941/ijddp.2024.100025

58 Downloaded
222 Viewed
5 Cited
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Open AccessReview
Transverse Tubules in Cardiac Health and Disease: Therapeutic Approaches to T-Tubule Remodelling and Heart Failure Management

Vanya Kalyan

2024, 3(4): 100024. doi: 10.53941/ijddp.2024.100024

29 Downloaded
192 Viewed
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Open AccessReview
Inhibiting the Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Cascade in Cancer and the Heart: for Better or Worse, in Sickness and Health?

Angela Clerk, Shona U Amadi, Samuel J Smith, Peter H Sugden

2024, 3(2): 100006. doi: 10.53941/ijddp.2024.100006

24 Downloaded
173 Viewed
2 Cited
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Open AccessReview
Small Leucine Rich Proteoglycan in Fibrotic Diseases: New Frenemies?

Jiayu Guo, Yan Wang, Haihai Liang, Baofeng Yang

2023, 2(2): 61-78. doi: 10.53941/ijddp.2023.100005

29 Downloaded
164 Viewed
5 Cited
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Open AccessArticle
Oxidized LDL Regulates Endothelin-1 and Oxidative Stress in Vascular Endothelial Cells: Role of Extracellular Regulated Kinase1/2 (ERK1/2)

Haishan Xu, Jinhong Duan, Jun Tao, Wen Wang, Yunqing Wu, Shunling Dai, Jun Ren

2023, 2(2): 18-29. doi: 10.53941/ijddp.2023.100002

32 Downloaded
168 Viewed
1 Cited
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Open AccessReview
Is miR-21 A Therapeutic Target in Cardiovascular Disease?

Antoinette Holland, Molly Enrick, Arianna Diaz, Liya Yin

2023, 2(1): 26-36. doi: 10.53941/ijddp.0201003

23 Downloaded
141 Viewed
25 Cited
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Open AccessReview
Targeting Inflammation to Control Tissue Fibrosis

Weihua Song, Wu Sun, Zilong Wang, Kelvin Yi Chong Teo, Chui Ming Gemmy Cheung, Xiaomeng Wang

2022, 1(1): 6. doi: 10.53941/ijddp.v1i1.206

12 Downloaded
114 Viewed
1 Cited
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