Articles

Articles

Open AccessReview

Rho/ROCK Pathway as a Therapeutic Target in Multiple Diseases

Zixiu Cheng, Shannon Erhardt, Jun Wang

2025, 4(3): 100018. doi: 10.53941/ijddp.2025.100018

43 Downloaded
302 Viewed
Download PDF
Open AccessReview

Alkaloids and Their Mechanisms of Action in Cardiovascular Diseases

Anil Kumar Prajapati, Gaurang Shah

2025, 4(3): 100017. doi: 10.53941/ijddp.2025.100017

38 Downloaded
203 Viewed
Download PDF
Open AccessArticle

The Effects and Mechanism of Guilu Bushen Pill in the Treatment of Osteoporosis Model in Ovariectomized Rats

Ximing Peng, Junjie Huang, Peifang Lai, Xiaorong Zhang, Mingdeng Guan, Xin Hu, Yimeng Ma, Meiqi Ji, Haiyan Gong, Chunhong Li, Xiuping Chen, Huaqian Wang

2025, 4(3): 100016. doi: 10.53941/ijddp.2025.100016

22 Downloaded
134 Viewed
Download PDF
Open AccessArticle
Analyzing the Structure-Activity Relationship of Necrostain-1 and Its Analogues as RIPK1 Inhibitors on Necroptosis

Huilin Liu, Heng Wang, Haoyi Zheng, Xiuping Chen

2025, 4(2): 100012. doi: 10.53941/ijddp.2025.100012

54 Downloaded
149 Viewed
Download PDF
Open AccessReview
Exploring Fungi Within the Human Gut Microbiota: Obstacles, Innovations, Therapeutic Applications and Prospects Ahead

Peng Xue, Chao Luo, Jiashu Li, Liang Yang, Yuanyuan Ma

2025, 4(2): 100007. doi: 10.53941/ijddp.2025.100007

36 Downloaded
97 Viewed
Download PDF
Open AccessReview
Research and Prospects on the Evaluation of Drug Cocrystal Permeability

Shuang Li, Meiru Liu, Dezhi Yang, Li Zhang, Yang Lu, Guanhua Du

2025, 4(1): 100005. doi: 10.53941/ijddp.2025.100005

34 Downloaded
86 Viewed
Download PDF
Open AccessArticle
Ginsenoside Re Alleviates Oxidative Stress Damage and Ferroptosis in Pulmonary Fibrosis Mice by Regulating the Nrf2/Keap1/GPX4 axis

Huicai Lin, Zhaoqin Wen, Linying Feng, Xiaoyan Chen, Yongxiang Song, Jiang Deng

2024, 3(4): 100025. doi: 10.53941/ijddp.2024.100025

23 Downloaded
69 Viewed
Download PDF
Open AccessReview
Inhibiting the Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Cascade in Cancer and the Heart: for Better or Worse, in Sickness and Health?

Angela Clerk, Shona U Amadi, Samuel J Smith, Peter H Sugden

2024, 3(2): 100006. doi: 10.53941/ijddp.2024.100006

12 Downloaded
63 Viewed
1 Cited
Download PDF
Open AccessReview
Small Leucine Rich Proteoglycan in Fibrotic Diseases: New Frenemies?

Jiayu Guo, Yan Wang, Haihai Liang, Baofeng Yang

2023, 2(2): 61-78. doi: 10.53941/ijddp.2023.100005

10 Downloaded
61 Viewed
3 Cited
Download PDF
Open AccessArticle
Oxidized LDL Regulates Endothelin-1 and Oxidative Stress in Vascular Endothelial Cells: Role of Extracellular Regulated Kinase1/2 (ERK1/2)

Haishan Xu, Jinhong Duan, Jun Tao, Wen Wang, Yunqing Wu, Shunling Dai, Jun Ren

2023, 2(2): 18-29. doi: 10.53941/ijddp.2023.100002

12 Downloaded
40 Viewed
Download PDF
Open AccessReview
Is miR-21 A Therapeutic Target in Cardiovascular Disease?

Antoinette Holland, Molly Enrick, Arianna Diaz, Liya Yin

2023, 2(1): 26-36. doi: 10.53941/ijddp.0201003

7 Downloaded
52 Viewed
17 Cited
Download PDF
Open AccessReview
Targeting Inflammation to Control Tissue Fibrosis

Weihua Song, Wu Sun, Zilong Wang, Kelvin Yi Chong Teo, Chui Ming Gemmy Cheung, Xiaomeng Wang

2022, 1(1): 6. doi: 10.53941/ijddp.v1i1.206

4 Downloaded
36 Viewed
1 Cited
Download PDF