IJDDP/
Articles

Articles

Open AccessReview

Myocardial Lipotoxicity in Cardiovascular Diseases: Mechanisms, Therapeutic Strategies, and Drug Target Discovery

Yaxin Xu, Xinrui Li, Lu Fu

2026, 5(2): 100009. doi: 10.53941/ijddp.2026.100009

1 Downloaded
8 Viewed
Download PDF
Open AccessEditorial

Nucleolar Stress: An Emerging Avenue for Cardiovascular Drug Target Identification

Tayyiba Azam, Xin Wang

2026, 5(1): 100007. doi: 10.53941/ijddp.2026.100007

22 Downloaded
81 Viewed
Download PDF
Open AccessReview

Strategic Engineering of Lipid Drug Carriers for the Treatment of Cancer

Shuyao Lang, Yunqing Li, Yi Kong, Youhai H. Chen

2025, 4(4): 100020. doi: 10.53941/ijddp.2025.100020

36 Downloaded
208 Viewed
Download PDF
Open AccessReview

Rho/ROCK Pathway as a Therapeutic Target in Multiple Diseases

Zixiu Cheng, Shannon Erhardt, Jun Wang

2025, 4(3): 100018. doi: 10.53941/ijddp.2025.100018

105 Downloaded
691 Viewed
Download PDF
Open AccessReview

The Underestimated Diabetic Cardiomyopathy: Its Role in Heart Failure Progression and Implications for Drug Discovery

Felycia Fernanda Hosyanto, Jiang Min, Suxin Luo, Shenglan Yang

2025, 4(3): 100015. doi: 10.53941/ijddp.2025.100015

36 Downloaded
178 Viewed
Download PDF
Open AccessReview
Targeting Cancer Drug-Tolerant Persister Cells in Minimal Residual Disease

Wei Zhang, Sorayut Chattrakarn, Fuhui Chen, Haobin Chai, Mariana Maranga, Jingwei Zhang

2025, 4(2): 100011. doi: 10.53941/ijddp.2025.100011

115 Downloaded
1127 Viewed
Download PDF
Open AccessReview
Short QT Syndrome and Drug Treatment: A systematic Literature Review and PRISMA Analysis

Tingting You, Cunjin Luo, Kevin Zhang, Henggui Zhang

2025, 4(2): 100009. doi: 10.53941/ijddp.2025.100009

49 Downloaded
174 Viewed
Download PDF
Open AccessArticle
Comparison of Thromboelastography, Conventional Coagulation Tests and Clotting Time in Preclinical Investigations of Anticoagulant Drugs in Rodents

Xinrong Yang, Boning Huang, Ping Tang, Liuqing Lin, Baoqin Lin

2025, 4(2): 100008. doi: 10.53941/ijddp.2025.100008

54 Downloaded
220 Viewed
Download PDF
Open AccessReview
Research and Prospects on the Evaluation of Drug Cocrystal Permeability

Shuang Li, Meiru Liu, Dezhi Yang, Li Zhang, Yang Lu, Guanhua Du

2025, 4(1): 100005. doi: 10.53941/ijddp.2025.100005

48 Downloaded
171 Viewed
Download PDF
Open AccessReview
Modeling Arrhythmia in a Dish: An Open View from Human-Engineered Heart Constructs

Shiya Wang, Pengcheng Yang, Jonathan Nimal Selvaraj, Donghui Zhang

2025, 4(1): 100001. doi: 10.53941/ijddp.2025.100001

34 Downloaded
533 Viewed
Download PDF
Open AccessReview
Human Cardiac Organoids: Quantification and Qualification in Cardiovascular Studies

Yingjuan Liu, Sabu Abraham, Honglin Xu

2024, 3(3): 100017. doi: 10.53941/ijddp.2024.100017

36 Downloaded
187 Viewed
Download PDF
Open AccessReview
Proteolysis Targeting Chimeras (PROTACs): An Innovative Strategy for Targeted Protein Degradation and Disease Treatment

Jun Xia, James K.S. Norris, May-Li MacKinnon, Sam Butterworth

2024, 3(3): 100015. doi: 10.53941/ijddp.2024.100015

47 Downloaded
164 Viewed
Download PDF
Open AccessReview
Cell Proliferation and Cytotoxicity Assays, The Fundamentals for Drug Discovery

Jingyi Niu, Minai Li, Ying Wang

2024, 3(3): 100013. doi: 10.53941/ijddp.2024.100013

309 Downloaded
1112 Viewed
7 Cited
Download PDF
Open AccessReview
Integrins as Drug Targets in Vascular and Related Diseases

Emily Meredith, Martin A. Schwartz

2024, 3(2): 100010. doi: 10.53941/ijddp.2024.100010

21 Downloaded
116 Viewed
2 Cited
Download PDF
Open AccessReview
Transforming Growth Factor β Signaling Pathway as a Potential Drug Target in Treating Aortic Diseases

Zijie Liu, Tianyu Song, Liping Xie

2024, 3(1): 100003. doi: 10.53941/ijddp.2024.100003

32 Downloaded
162 Viewed
1 Cited
Download PDF
Open AccessReview
The Role of Macrophages in Orthodontic Tooth Movement: A Review

Weiye Zhao, Hao Xu, Hanwen Zhang, Bin Yan

2023, 2(3): 97-104. doi: 10.53941/ijddp.2023.100008

20 Downloaded
104 Viewed
Download PDF
Open AccessExpert review
p21-Activated Kinases Present a New Drug Target for Hypertrophic Cardiomyopathy

Yu He, Ming Lei

2023, 2(3): 79-86. doi: 10.53941/ijddp.2023.100006

17 Downloaded
81 Viewed
1 Cited
Download PDF
Open AccessReview
Mechanism of Anti-seizure Medications and Emerging Trends in Epilepsy Treatment

Zubin Singh Rana, Reena Suman, Shobi Veleri, Pradeep Punnakkal

2023, 2(2): 1-16. doi: 10.53941/ijddp.2023.100001

95 Downloaded
318 Viewed
Download PDF
Open AccessReview
Controlled and Targeted Drug Delivery Using Smart Nanovectors

Abou Bakr M. Salama, Yasmin Y. Salem, Tamer M. A. Mohamed

2023, 2(1): 18-25. doi: 10.53941/ijddp.0201010

29 Downloaded
276 Viewed
3 Cited
Download PDF
Open AccessReview
The Therapeutic Effects of Ligustrazine in Combination with Other Drugs in Cardiovascular Diseases

Peihua Dong, Yu Huang, Yujie Pu

2023, 2(1): 11-17. doi: 10.53941/ijddp.0201005

11 Downloaded
89 Viewed
Download PDF
Open AccessReview
Biological Functions and Applications of Exosomes in Drug Research

Mengmeng Fu, Jiapeng Li, Tungalag Battulga, Xiaoxue Li, Ming Xu

2023, 2(1): 85-90. doi: 10.53941/ijddp.0201008

15 Downloaded
69 Viewed
Download PDF
Open AccessEditorial
Current Progress in Drug Target Identification and Drug Delivery

Xin Wang

2022, 1(1): 1. doi: 10.53941/ijddp.v1i1.214

18 Downloaded
67 Viewed
Download PDF
Open AccessMini Review
Injectable Multifunctional Natural Polymer-Based Hydrogels for the Local Delivery of Therapeutic Agents

Xue Bai, Annalisa Tirella

2022, 1(1): 10. doi: 10.53941/ijddp.v1i1.203

26 Downloaded
151 Viewed
Download PDF
Open AccessReview
Advances of the Target-Based and Phenotypic Screenings and Strategies in Drug Discovery

Shoubao Wang, Zihan Wang, Lianhua Fang, Yang Lv, Guanhua Du

2022, 1(1): 2. doi: 10.53941/ijddp.v1i1.199

72 Downloaded
311 Viewed
10 Cited
Download PDF
Open AccessReview
The Hippo Signaling Pathway as a Drug Target in Familial Dilated Cardiomyopathy

Paulina Langa, Beata M. Wolska, R. John Solaro

2022, 1(1): 4. doi: 10.53941/ijddp.v1i1.189

9 Downloaded
55 Viewed
6 Cited
Download PDF
Open AccessReview
Progress of 3D Organoid Technology for Preclinical Investigations: Towards Human In Vitro Models

Yingjuan Liu, Honglin Xu, Sabu Abraham, Xin Wang, Bernard D. Keavney

2022, 1(1): 9. doi: 10.53941/ijddp.v1i1.188

27 Downloaded
125 Viewed
3 Cited
Download PDF
Open AccessReview
Nanoparticle-based Drug Delivery System for Post Myocardial Infarction Management

Minxuan Liu, Chiara Ramponi, Xiaoxue Fan, Xinzhuang Zhang, Liang Cao, Zhenzhong Wang, Wei Xiao

2022, 1(1): 11. doi: 10.53941/ijddp.v1i1.171

15 Downloaded
81 Viewed
2 Cited
Download PDF