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Open AccessReview

GPCR Biased Signaling: Conceptual Advancements and Therapeutic Innovation

Supeng Li, Yongyin Huang, Xingsheng Sun, Ao Shen

2026, 5(2): 100011. doi: 10.53941/ijddp.2026.100011

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Open AccessReview

Myocardial Lipotoxicity in Cardiovascular Diseases: Mechanisms, Therapeutic Strategies, and Drug Target Discovery

Yaxin Xu, Xinrui Li, Lu Fu

2026, 5(2): 100009. doi: 10.53941/ijddp.2026.100009

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Open AccessReview

Natural Products Targeting GLP-1: Insights into Herbal Therapy for Insulin Resistance and Beta-Cell Function

Akshita Vyas, Shraddha Mahajan, Sumeet Dwivedi, Sweta S. Koka, Gajanan N. Darwhekar

2026, 5(1): 100001. doi: 10.53941/ijddp.2026.100001

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Open AccessReview

The Role and Therapeutic Potential of ARSB Gene in Tumor Development

Zhiqiang Zhang, Qunlong Jin, LiangJin Zhang, Junyao Wan, Yunfei Gao, Ningning Li, Haitao Wang, Yulong He, Xin Zhong

2025, 4(4): 100023. doi: 10.53941/ijddp.2025.100023

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Open AccessReview

RhoA/ROCK Signaling in Vascular Dysfunction: Emerging Insights and Therapeutic Perspectives

Xiao Du, Weijia Luo, Jiang Chang

2025, 4(4): 100022. doi: 10.53941/ijddp.2025.100022

44 Downloaded
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1 Cited
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Open AccessReview

Finerenone Targeting the Mineralocorticoid Receptor: Therapeutic Potential for Cardiorenal Syndrome

Hairui Zhao, Chunyv Pan, Xiaojing Cai, Manyi Wu, Bowen Qin, Hui Zhang, Hengzhi Du, Junhua Li

2025, 4(4): 100019. doi: 10.53941/ijddp.2025.100019

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Open AccessReview

Rho/ROCK Pathway as a Therapeutic Target in Multiple Diseases

Zixiu Cheng, Shannon Erhardt, Jun Wang

2025, 4(3): 100018. doi: 10.53941/ijddp.2025.100018

124 Downloaded
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Open AccessReview
Exploring Fungi Within the Human Gut Microbiota: Obstacles, Innovations, Therapeutic Applications and Prospects Ahead

Peng Xue, Chao Luo, Jiashu Li, Liang Yang, Yuanyuan Ma

2025, 4(2): 100007. doi: 10.53941/ijddp.2025.100007

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Open AccessReview
Coronary Microvascular Dysfunction: A Potential Intervention Strategy against Acute Myocardial Infarction

Zihan Wang, Lianhua Fang, Yang Lv, Shoubao Wang, Guanhua Du

2025, 4(1): 100004. doi: 10.53941/ijddp.2025.100004

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Open AccessReview
Transverse Tubules in Cardiac Health and Disease: Therapeutic Approaches to T-Tubule Remodelling and Heart Failure Management

Vanya Kalyan

2024, 3(4): 100024. doi: 10.53941/ijddp.2024.100024

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Open AccessReview
Immune Checkpoints Are New Therapeutic Targets in Regulating Cardio-, and Cerebro-Vascular Diseases and CD4+Foxp3+ Regulatory T Cell Immunosuppression

Ying Shao, William Y. Yang, Gayani Nanayakkara, Fatma Saaoud, Mohammed Ben Issa, Keman Xu, Yifan Liu, Xiaohua Jiang, Sadia Mohsin, Hong Wang, Xiaofeng Yang

2024, 3(4): 100022. doi: 10.53941/ijddp.2024.100022

21 Downloaded
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6 Cited
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Open AccessReview
The Role of Autophagy in Heart Disease

Osman Mohiuddin, Sabu Abraham, Hongyuan Zhang, Andrea Ruiz-Velasco

2024, 3(4): 100021. doi: 10.53941/ijddp.2024.100021

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1 Cited
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Open AccessReview
Adrenergic Regulation of Cardiac Macrophages: Heterogeneity, Plasticity, and Therapeutic Potential

Wenjing Xiang, Mianli Wang, Hualong Yu, Haocheng Lu, Ying Wang

2024, 3(4): 100020. doi: 10.53941/ijddp.2024.100020

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Open AccessReview
Molecular and cellular contributors of Rheumatoid Arthritis

Qingxin Bang, Weihua Song, Xiaomeng Wang

2024, 3(3): 100018. doi: 10.53941/ijddp.2024.100018

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Open AccessReview
Integrins as Drug Targets in Vascular and Related Diseases

Emily Meredith, Martin A. Schwartz

2024, 3(2): 100010. doi: 10.53941/ijddp.2024.100010

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2 Cited
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Open AccessReview
The Role of the CREB Signaling Pathway in Tumor Development and Therapeutic Potential

Qunlong Jin, Youheng Jiang, Zhiheng Zhang, Yanming Yang, Zhang Fu, Yunfeng Gao, Ningning Li, Yulong He, Changxue Li

2024, 3(2): 100011. doi: 10.53941/ijddp.2024.100011

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Open AccessReview
Emerging and Novel Therapeutic Treatments Targeting Mitochondrial-Endoplasmic Reticulum Contact Sites in Metabolic and Vascular Disorders

Richard M. Monaghan

2024, 3(2): 100008. doi: 10.53941/ijddp.2024.100008

48 Downloaded
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Open AccessReview
Hippo Signaling: Advances in Potential Therapeutic Targets for Sinoatrial Node Disorders

Julianna N. Quinn, Jun Wang

2023, 2(4): 36-43. doi: 10.53941/ijddp.2023.100014

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Open AccessReview
The Therapeutic Effects of Ligustrazine in Combination with Other Drugs in Cardiovascular Diseases

Peihua Dong, Yu Huang, Yujie Pu

2023, 2(1): 11-17. doi: 10.53941/ijddp.0201005

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Open AccessReview
Recent Clinical Successes in Liposomal Nanomedicines

Wenjie Gu, Gavin P. Andrews, Yiwei Tian

2023, 2(1): 52-59. doi: 10.53941/ijddp.0201009

38 Downloaded
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15 Cited
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Open AccessReview
Is miR-21 A Therapeutic Target in Cardiovascular Disease?

Antoinette Holland, Molly Enrick, Arianna Diaz, Liya Yin

2023, 2(1): 26-36. doi: 10.53941/ijddp.0201003

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22 Cited
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Open AccessReview
Promising Treatments for Duchenne Muscular Dystrophy: Restoring Dystrophin Protein Expression Using Nucleic Acid Therapeutics

Guo Hu, Chen Chen

2023, 2(1): 4-10. doi: 10.53941/ijddp.0201002

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Open AccessMini Review
Injectable Multifunctional Natural Polymer-Based Hydrogels for the Local Delivery of Therapeutic Agents

Xue Bai, Annalisa Tirella

2022, 1(1): 10. doi: 10.53941/ijddp.v1i1.203

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Open AccessReview
The P21-Activated Kinase 1 and 2 As Potential Therapeutic Targets for the Management of Cardiovascular Disease

Honglin Xu, Dingwei Wang, Chiara Ramponi, Xin Wang, Hongyuan Zhang

2022, 1(1): 5. doi: 10.53941/ijddp.v1i1.179

21 Downloaded
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6 Cited
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Open AccessReview
From Bench to Bedside: Current Developments in RNA-Based Therapies for Treatment of Hyperlipidemia

Yufei Zhou, Chen Chen

2022, 1(1): 7. doi: 10.53941/ijddp.v1i1.141

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