Articles

Articles

Open AccessArticle

Gamma-Glutamyl Hydrolase (GGH) Overexpression in Luminal B Breast Cancer: A New Marker of Aggression and a Therapeutic Target

Radjaa Regad, Amina Belhadj, Sonia Amel Sedikki, Sabrina Khelifa, Zakaria Merad, Sarah Hayat Bouasaba, Tewfik Sahraoui

2026, 3(2): 7. doi: 10.53941/hm.2026.100014

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Open AccessOpinion

Inflammatory Bursts as Stochastic Triggers in Cancer Initiation

Xiuli Zhang, Qingshui Wang, Yao Lin

2026, 3(2): 6. doi: 10.53941/hm.2026.100013

23 Downloaded
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Open AccessReview

Artificial Intelligence Empowers Monitoring, Assessment, and Management in Exercise

Min Zhu, Yuhuai Guo, Mingliang Zhao, Tao Sun, Rengfei Shi, Xiaojiao Zheng, Tianlu Chen

2026, 3(2): 5. doi: 10.53941/hm.2026.100012

44 Downloaded
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Open AccessReview

Iron-Dependent Regulation of Tryptophan Metabolism in Depression

Yan Zhang, Jinping Liu, Mingqian Fang, Ren Lai

2026, 3(2): 4. doi: 10.53941/hm.2026.100011

23 Downloaded
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Open AccessReview

Interplay between Gut Microbiome, Metabolites, and Tumor Immunity: Mechanisms and Clinical Translation

Zhen Zhang, Yongchao Gao, Fengyan Yuan, Quanlin Wang, Wei Zhang, Rong Liu

2026, 3(2): 3. doi: 10.53941/hm.2026.100010

31 Downloaded
108 Viewed
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Open AccessReview

Mitochondria in Cardiac Disease: Mechanisms, Therapeutic Targets, and Clinical Progress

Edric X. Zhang, Lucas J. Wang, Shen Hu

2026, 3(2): 2. doi: 10.53941/hm.2026.100009

51 Downloaded
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Open AccessReview

NLRP3 Inflammasome: A Potential Therapeutic Target for Atherosclerosis

Mengqi Wang, Jun Cheng, Fen Feng, Linxi Chen

2026, 3(2): 1. doi: 10.53941/hm.2026.100008

43 Downloaded
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Open AccessReview

Monocytes, Macrophages, and Exercise Prescription: A New Frontier in Immunomodulation

Tan Zhang, Li-Hao Huang

2026, 3(1): 7. doi: 10.53941/hm.2026.100007

72 Downloaded
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Open AccessReview

Progress in Henipavirus Neutralizing Antibody for Therapeutic Development

Junping Hong, Yuanteng Zhao, Ethan H. Zhou, Eleni Kourlas, Zhangfei Shen, Kai Xu

2026, 3(1): 6. doi: 10.53941/hm.2026.100006

76 Downloaded
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Open AccessReview

GLP-1 Receptor Agonists for Weight Control: Emerging Insights from Clinical Trials and Future Perspectives

Jiayao Lv, Shiyi Zhang, Yizhe Qu, Youshen Cao, Jiayi Zhang, Xiaoshuang Dai, Lin Shi

2026, 3(1): 5. doi: 10.53941/hm.2026.100005

62 Downloaded
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Open AccessReview

Enabling Live Single-Cell Metabolomics: Mass Spectrometry Technologies and Functional Applications

Simin Cheng, Danni Wu, Xiaoxiao Ma, Xiaoyun Gong

2026, 3(1): 4. doi: 10.53941/hm.2026.100004

102 Downloaded
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Open AccessArticle

Multi-Omics Analysis Reveals Crosstalk between Signaling and Metabolic Reprogramming during Celastrol-Mediated Inflammatory Response

Guangshan Xie, Lin Zhu, Xin Diao, Xiuli Su, Li Zhong, Zongwei Cai

2026, 3(1): 3. doi: 10.53941/hm.2026.100003

58 Downloaded
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Open AccessReview

A Narrative Review of Sarcopenic Obesity in the Elderly: Pathogenesis and Treatment Strategies

Haiwang Shi, Tao Wu, Rui Duan

2026, 3(1): 2. doi: 10.53941/hm.2026.100002

74 Downloaded
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Open AccessReview

Applications of HP-CIL Metabolomics Technology: Advances and Future Perspectives

Jia Li, Cheng Chen, Xingyu Wang, Xi Chen, Jingjing Zhan, Shuang Zhao, Liang Li

2026, 3(1): 1. doi: 10.53941/hm.2026.100001

39 Downloaded
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Open AccessReview

Diverse Mechanisms of Saturated Fatty Acids in Cardiovascular Disease

Xiaoshan Huang, Dawit Adisu Tadese, Qiumin Lu, Ren Lai

2025, 2(4): 9. doi: 10.53941/hm.2025.100032

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Open AccessArticle

An Observational Study on the Associations between Arterial Stiffness and Health-Related Physical Fitness in Young Adults

Long-Long Liu, Jing Zhang, Qian Xie, Yuan Zhou, Bo Ye, Wan-Wan Wang, Wen-Xin Wei, Liang-Liang Yan, Xiao-Long Li

2025, 2(4): 7. doi: 10.53941/hm.2025.100030

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Open AccessArticle

Moderate, Rather than Vigorous Exercise Improves Plasma Amino Acid Profiles in Patients with Nonalcoholic Fatty Liver Disease

Jia Li, Weijuan Su, Caoxin Huang, Zheng Chen, Shunhua Wang, Yan Zhao, Zhong Chen, Xiulin Shi, Xuejun Li

2025, 2(4): 5. doi: 10.53941/hm.2025.100028

41 Downloaded
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Open AccessReview

Riboswitch Dynamics and Their Expanding Biotechnological Applications

Dian Chen, Yu Liu

2025, 2(4): 4. doi: 10.53941/hm.2025.100027

64 Downloaded
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1 Cited
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Open AccessReview

Fermented Foods Strengthen Immunity against Viral Infections

Xiaoqian Zhou, Binyu Cui, Xiaoyu Wang, Aman Khan, Weidong Wang

2025, 2(4): 3. doi: 10.53941/hm.2025.100026

33 Downloaded
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Open AccessReview

In Vivo Electrochemical Biosensors: Technology and Personalized Medicine Go Hand in Hand

Yuxin Lou, Siting Chen, Shijin Peng, Fei Lan, Zhuowei Gao, Ye Zhang, Min Luo

2025, 2(4): 2. doi: 10.53941/hm.2025.100025

32 Downloaded
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Open AccessReview
Autophagy: A Major Regulatory Factor in Glucose Metabolism

Meiqing Liu, Xuling Luo, Haoliang Hu, Linxi Chen

2025, 2(4): 1. doi: 10.53941/hm.2025.100024

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Open AccessArticle
A Sialic Acid-Caged Generic Platform for Sialoengineering of Tumors with Artificial Immuno-Ligand

Shuo Zhang, Huiling Dong, Shixiong Wen, Zejing Lin, Xuanjun Wu, Jiahuai Han, Shoufa Han

2025, 2(3): 8. doi: 10.53941/hm.2025.100023

131 Downloaded
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Open AccessReview
From Liver to Muscle: Crosstalk Mechanisms and Interventions in Sarcopenia

Qiquan Wang, Meng Yao, Xiang Wang, Xinqiang Lan, Gailing Fan, Yang Xiang

2025, 2(3): 7. doi: 10.53941/hm.2025.100022

109 Downloaded
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Open AccessReview
Cas9 Cis/Trans Cleavage Mechanisms: Cross-System CRISPR Insights and Diagnostic Applications

Xueying Li, Ying Chen, Linglong Huang, Jiyun Chen, Liang Liu

2025, 2(3): 6. doi: 10.53941/hm.2025.100021

35 Downloaded
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1 Cited
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Open AccessArticle
Comparative Study on Metabolic Regulation of SAP Deletion in Normal Mice and Atherosclerotic Mice

Yifan Zhu, Shuhan Xie, Hailong Shu, Yiqing Lu, Jiawei Guo, Qian Li, Yongli Zhang, Yongxia Yang

2025, 2(3): 5. doi: 10.53941/hm.2025.100020

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Open AccessReview
Gastrointestinal Microbial Involvement in Gallstone Formation: A Systematic Review

Sirui Wan, Kun Xia, Yunpeng Liu, Hongzhi Xu

2025, 2(3): 3. doi: 10.53941/hm.2025.100018

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Open AccessArticle
Metabolomics and Lipidomics Study Reveals Metabolic Dysregulation in Epididymal Adipose Tissue of db/db Mice

Yi Ru, Li Xiang, Qing Shen, Xiuli Su, Aimin Xu, Zongwei Cai

2025, 2(3): 1. doi: 10.53941/hm.2025.100016

60 Downloaded
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Open AccessReview
Pathogenic Mechanisms and Treatment Advancements of Sjogren’s Syndrome

Derica C. Tang, Shen Hu

2025, 2(2): 8. doi: 10.53941/hm.2025.100015

65 Downloaded
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Open AccessReview
Application of LLMs/Transformer-Based Models for Metabolite Annotation in Metabolomics

Yijiang Liu, Feifan Zhang, Yifei Ge, Qiao Liu, Siyu He, Xiaotao Shen

2025, 2(2): 7. doi: 10.53941/hm.2025.100014

165 Downloaded
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6 Cited
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Open AccessReview
The Metabolic Underpinnings of Retinal Health and Disease: A Focus on Photoreceptor Cells

Jianbo Jin, Qiuping Liu, Cheng Li

2025, 2(2): 6. doi: 10.53941/hm.2025.100013

49 Downloaded
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Open AccessReview
Strategies for Tag Design and Removal in the Expression and Purification of Recombinant Proteins

Jiayi Xie, Hongyi Fan, Qingshan Bill Fu

2025, 2(2): 4. doi: 10.53941/hm.2025.100011

193 Downloaded
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1 Cited
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Open AccessReview
Targeting Cellular DNA Damage Response in Cancer and Bacterial Infections: Current Progress, Challenges, and Opportunities

Ranxun Lin, Xu Zhang, Qinwei Zhu, Xuening Chen, Lin Dai, Longheng Li, Zuoan Li, Zhonghui Lin

2025, 2(2): 3. doi: 10.53941/hm.2025.100010

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Open AccessArticle
Vascular and Metabolic Responses to Elevated Circulating PDGF-BB in Mice: A Multiparametric MRI Study

Xiuli Yang, Jiekang Wang, Yuguo Li, Mei Wan, Zhiliang Wei

2025, 2(2): 2. doi: 10.53941/hm.2025.100009

63 Downloaded
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Open AccessReview
From Clinical to Basic Research: The Neuroprotective Effects and Mechanisms of Caffeine

Lijing Wang, Linxi Wang

2025, 2(2): 1. doi: 10.53941/hm.2025.100008

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1 Cited
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Open AccessReview
Application of Wearable Devices in Diabetes Management

Zijing Du, Feifan Zhang, Yifei Ge, Yijiang Liu, Honghua Yu, Yong Wang, Rinkoo Dalan, Xiaotao Shen

2025, 2(1): 7. doi: 10.53941/hm.2025.100007

144 Downloaded
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5 Cited
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Open AccessReview
Structural Overview of Herpesvirus Tegument Proteins

Hui-Ping He, Shuang Liao, Dong-Dong Gu, Kun Shi, Song Gao

2025, 2(1): 6. doi: 10.53941/hm.2025.100006

56 Downloaded
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Open AccessReview
Lifting the Veil on Myeloma Bone Disease

Rui Chen, Rui Liu, Huan Liu

2025, 2(1): 5. doi: 10.53941/hm.2025.100005

16 Downloaded
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Open AccessReview
AMPK-Mediated Multi-Organ Protective Effects of GLP-1 Receptor Agonists

Xin Wang, Linxi Wang

2025, 2(1): 4. doi: 10.53941/hm.2025.100004

72 Downloaded
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2 Cited
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Open AccessReview
Effects of Static Magnetic Fields on Metabolic Diseases

Shiyu Lu, Junjun Wang, Xin Zhang

2025, 2(1): 3. doi: 10.53941/hm.2025.100003

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Open AccessReview
Gut Microbiota and Their Metabolites as Modulators of Vascular Complications in Diabetes

Meng Duan, Jielu Wen, Anning Chen, Sifan Chen

2025, 2(1): 2. doi: 10.53941/hm.2025.100002

40 Downloaded
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1 Cited
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Open AccessReview
Key Factors in the Multiple Mechanisms of Virus Entry

Yifan Wang, Quanxiang Yu, Shuru Lin, Wenqi Jiang, Zhengfei Qi, Lina Wang, Lian Wu, Rui Ma, Kexin Zhang, Shurong Chen, Jiayi Xie, Lingli Zheng, Min Zhou, Qingshan Bill Fu

2025, 2(1): 1. doi: 10.53941/hm.2025.100001

54 Downloaded
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Open AccessReview
RNA Devices for Therapeutic Applications: Progress, Challenges and Future Perspective

Vibha Dwivedi, Yun-Xing Wang

2024, 1(1): 7. doi: 10.53941/hm.2024.100007

52 Downloaded
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Open AccessReview
Endoplasmic Reticulum Unfolded Protein Responses: Molecular Mechanism and Role in Pathophysiology

Miankun Wu, Fen Feng, Jiangang Cao, Linxi Chen

2024, 1(1): 6. doi: 10.53941/hm.2024.100006

31 Downloaded
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Open AccessReview
Asymmetric Cell Division and Satellite Cell Fate Regulation in Skeletal Muscle Aging and Disease

Shenghe Wang, Guangchuang Yu, Liwei Xie

2024, 1(1): 5. doi: 10.53941/hm.2024.100005

49 Downloaded
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Open AccessReview
The Multifaced Roles of Hepatic Macrophages in MASLD

Xiaoping Sui, Minqi Wu, Xue Yang, Yanan Wang

2024, 1(1): 4. doi: 10.53941/hm.2024.100004

26 Downloaded
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